Christian McCaffrey's big night leads 49ers to 20-9 victory over Panthers SANTA CLARA, Calif. (AP) — Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three years ago. McCaffrey gained 142 yards from scrimmage and scored a touchdown to help the 49ers beat the Panthers 20-9 on Monday night. He helped the Niners overcome three interceptions in the first half by Brock Purdy.