CINCINNATI--(BUSINESS WIRE)--Sep 17, 2025-- Fifth Third Bank, National Association (Nasdaq: FITB) today announced it will decrease its prime lending rate to 7.25%, effective immediately. The rate was last changed on December 18, 2024, when Fifth Third decreased its prime lending rate from 7.75% to 7.50%. About Fifth Third Fifth Third is a bank that’s as long on innovation as it is on history.