49ers look to improve to 4-0 when they host the Jaguars without Nick Bosa - The Morning Sun

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49ers look to improve to 4-0 when they host the Jaguars without Nick Bosa

San Francisco 49ers' Mykel Williams (98) pressures Arizona Cardinals' Kyler Murray, left, into an intentional grounding penalty while in the end zone in the second half of an NFL football game in Santa Clara, Calif., Sunday, Sept. 21, 2025. - photo by Carlos Avila Gonzalez/San Francisco Chronicle via AP

San Francisco 49ers' Mykel Williams (98) pressures Arizona Cardinals' Kyler Murray, left, into an intentional grounding penalty while in the end zone in the second half of an NFL football game in Santa Clara, Calif., Sunday, Sept. 21, 2025. - photo by Carlos Avila Gonzalez/San Francisco Chronicle via AP

Jacksonville (2-1) at San Francisco (3-0) Sunday, 4:05 p.m. EDT, Fox. BetMGM NFL Odds: 49ers by 3. Against the spread: Jaguars 2-1; 49ers 2-1.

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